Program for Breakthough Biomedical Research

Types of Awards

Call for Proposals

Recent Awards

Program Reports


2009 Awardees

Opportunity Awards

     Synthetic Cell Biology
Zev Gartner, Ph.D. (Pharmaceutical Chemistry)
     Understanding the Embryonic Germ Cell Niche, Toward Improved In Vitro Gametogenesis
Diana Laird, Ph.D. (Institute for Regeneration Medicine and Obstetrics, Gynecology, and Reproductive Science)
     Biophysical Survey of All Known Bacterial Actin-Like Proteins
R. Dyche Mullins, Ph.D. (Cellular and Molecular Pharmacology)
     Role of SIRT1 in the Immune System
Melanie Ott, M.D., Ph.D. (Medicine)
     In Vivo Chemical-Genetic Analysis of CDK Function
Andrei Goga, M.D., Ph.D. (Medicine)
     Solving the Architecture of Macromolecular Complexes with Super-Resolution Fluorescence Microscopy
Bo Huang, Ph.D. (Pharmaceutical Chemistry)
     Imaging the Balance of Excitation and Inhibition in the Brain
Susan Voglmaier, M.D., Ph.D. (Psychiatry)

New Technology

     Novel Tools for Probing Glutamatergic Synaptic Transmission and Plasticity
Pamela England, Ph.D. (Pharmaceutical Chemistry)
      An Open Source Whole Genome Mouse RNAi Library
Michael McManus, Ph.D. (Diabetes Center and Microbiology & Immunology)

Integrative Research Awards

     Genetic Analysis of Vocal Learning
Michael Brainard, Ph.D. (Physiology), Jane Gitschier, Ph.D. (Medicine and Pediatrics), Steven Hamilton, M.D., Ph.D. (Psychiatry)
     Defining the Metabolic Consequences of Autophagy Using Magnetic Resonance Spectroscopy (MRS)
Jayanta Debnath, M.D. (Pathology), Sabrina Ronen, Ph.D. (Radiology and Biomedical Imaging)
     Defining Roles on N-Glycans in Endoplasmic Reticulum-Mediated Quality Control
Danica Galonić Fujimori, Ph.D. (Cellular and Molecular Pharmacology), Jonathan Weissman, Ph.D. (Cellular and Molecular Pharmacology)
     Cerebral Connectivity and the Autistic Spectrum: Linking Genes to Anatomy and Behavior in Patients with Agenesis of the Corpus Callosum
Elliott Sherr, M.D., Ph.D. (Neurology), Pratik Mukherjee, M.D., Ph.D. (Radiology), Srikantan Nagarajan, Ph.D. (Radiology)
     Using Small Molecular Screens in Whole Animals to Identify Modulators of Drug Partition
Roland Bainton, M.D., Ph.D. (Anesthesia), Kaveh Ashrafi, Ph.D. (Physiology)
     In Vivo Characterization of the Vertebrate Regulatory Code
Katherine Pollard, Ph.D. (Epidemiology and Biostatistics), Nadav Ahituv, Ph.D. (Bioengineering and Therapeutic Sciences)

UCSF Fellow

      Richard Deneman, Ph.D. (Anatomy)

Independent Postdoctoral Fellow Research

     BDNF-TrkB Signaling and the Assembly of Inhibitory Circuits in the Developing Retina
Albert Chen, Ph.D. (Physiology)
     Understanding the Role of NKG2D Ligands in Patients with Recurrent Gliobastoma
Courtney Crane, Ph.D. (Neurosurgery)
     The Cellular Mechanisms Controlling Normal Protein Aggregation with Age
Della David, Ph.D. (Biochemistry and Biophysics)
     In Vivo Analysis of Axonal Transport and Synaptogenesis in Zebrafish Retinotectal Projections
Filippo Del Bene, Ph.D. (Physiology)
     New Pharmacological Tools to Study the Role of Dopamine Receptors in Addiction
Jim Fleming, Ph.D. (Pharmaceutical Chemistry)
     Nucleosome Arrangement and the Spread of Heterochromatin
Andrew Horwitz, Ph.D., Basseem Al-Sady, Ph.D. (Biochemistry and Biophysics)
     Developing Genome-Wide Mixed-Pool shRNA Libraries to Identify Components in Apoptotic Signaling in Immune Cells
Robert Jan Lebbink, Ph.D. (Diabetes Center)
     A Molecular Genetic Dissection of the Neural Substrates of Social Attachment in the Prairie Vole M. Ochrogaster
Devanand Manoli, M.D., Ph.D. (Anatomy)
     How Social Experience Leads to Changes in Behavior
Galit Ophir, Ph.D. (Anatomy)
     MAPK Signaling Regulates Self-Renewal and Differentiation in Glioma
Anders Persson, Ph.D. (Neurology)
     PRMT1 in the Regulation of BMP Signaling During Drosophila Wing Morphogenesis
Jian Xu, Ph.D. (Cell & Tissue Biology)
     Investigation of the Unfolded Protein Response and its Effects on Breast Cancer
John Paul Upton, Ph.D. (Pathology)
     Identification of β-Catenin/Transcription Factor Machinery from ES Cell
Fumiaki Yumoto, Ph.D. (Biochemistry and Biophysics)
     Investigating the Function of Mushroom Body Local GABAergic Interneurons in Drosophila Olfactory Processing
Sijun Zhu, M.D, Ph.D. (Physiology)